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Protect Kidneys from Glomerular Diseases

Biopsy-guided care, steroid-sparing regimens, and relapse prevention led by glomerular experts

Book Glomerular Clinic
89%
Remission Achieved
Within 6 months for steroid-responsive cases
7 days
Biopsy Turnaround
Pathology report with immunofluorescence
3.2%
Relapse Rate
Sustained with maintenance therapy

When to Consult

  • Swelling of face, ankles, or abdomen
  • Frothy urine or heavy protein loss
  • High blood pressure with kidney inflammation markers
  • Relapse after prior nephrotic syndrome remission
  • Blood in urine or unexplained kidney dysfunction
  • Systemic symptoms like rash, joint pains, or fevers

Understanding Nephrotic Syndrome & Glomerulonephritis in India

Glomerular diseases account for nearly 30% of chronic kidney disease in younger Indians. Frequent infections, genetic predispositions, and delayed biopsies increase complications. Ajuda Hospitals offers rapid diagnostics and precise immunotherapy tailored to histological subtypes, enabling remission while limiting steroid exposure.

Families from Hyderabad, Warangal, and Karimnagar trust our bilingual counselling to explain complex biopsy reports and medication schedules. We prioritise early intervention so students and working professionals can resume routines with confidence.

When to Consult Our Glomerular Specialists

⚠️ Seek Immediate Care If You Experience:

  • ✓ Sudden facial or leg swelling with frothy urine
  • ✓ Dark or blood-stained urine
  • ✓ Severe hypertension or headaches
  • ✓ Breathlessness or abdominal distension due to fluid

Consult Ajuda if previous nephrotic syndrome is relapsing, biopsy reports are pending interpretation, or systemic symptoms suggest autoimmune involvement. Early treatment prevents scarring and chronic kidney disease.

Our Diagnostic Approach

Comprehensive Labs

We quantify proteinuria, assess albumin levels, and screen for autoimmune markers (ANA, dsDNA, ANCA) and infections (HBV, HCV) to rule out secondary causes.

Imaging Support

Renal ultrasound evaluates size, structure, and venous flow. Doppler helps detect renal vein thrombosis in severe nephrotic syndrome.

Ultrasound-Guided Biopsy

Experienced nephrologists perform day-care biopsies with minimal discomfort. Samples undergo light microscopy, immunofluorescence, and electron microscopy when needed.

Multidisciplinary Review

Biopsy results are discussed with pathologists, intensivists, and rheumatologists to craft precise regimens considering fertility, pregnancy, or comorbidities.

Treatment Pathways

Our protocols align with KDIGO 2021 guidance:

  • Steroid & Immunosuppressive Therapy: Prednisolone, tacrolimus, MMF, rituximab, or cyclophosphamide based on diagnosis.
  • Supportive Care: ACE inhibitors/ARBs, diuretics, statins, and anticoagulation when needed.
  • Plasma Exchange: For anti-GBM disease or severe ANCA vasculitis with pulmonary haemorrhage.
  • Lifestyle & Nutrition: Tailored salt restriction, adequate protein intake, and vaccine schedules.
  • Relapse Prevention: Home urine monitoring, tele check-ins, and rapid steroid restart plans.
  • Long-term Surveillance: Annual CKD screening and bone health assessments to manage therapy side effects.

What to Expect: Your Care Journey

  1. Initial Evaluation: Clinical assessment, labs, and biopsy scheduling explained in detail.
  2. Diagnosis & Treatment Start (Week 1): Biopsy report discussed, personalised medication plan initiated, and side-effect counselling provided.
  3. Induction Phase (Week 4-8): Close monitoring of proteinuria, albumin levels, and blood pressure; adjust immunosuppressants.
  4. Maintenance & Follow-up (Month 3 onwards): Monthly checks taper to quarterly reviews once remission sustained, with tele support for rural patients.

Technology & Innovation

Our Glomerular Disease Registry captures biopsy subtype, medication course, and outcomes. Automated alerts flag overdue labs or rising protein, enabling faster response. Patients access bilingual education videos via WhatsApp for self-testing and symptom tracking.

Preventing Complications

Vaccination protocols, prophylactic antibiotics, and glucose monitoring minimise steroid side effects. Bone health clinics prevent osteoporosis. Anticoagulation is considered for severe hypoalbuminaemia to avoid thrombosis.

Why Ajuda for Glomerular Care?

🔬 Rapid Biopsy Access

Day-care biopsies with 7-day pathology including immunofluorescence for precise diagnosis.

🛡️ Steroid-Sparing Strategies

Use of rituximab, tacrolimus, and MMF reduces long-term side effects.

📞 Always-On Support

Tele follow-ups and WhatsApp symptom tracking keep relapses in check.

Take the First Step

If you or your child shows signs of nephrotic syndrome or glomerulonephritis, act early. Call 9010550550 or message Ajuda Hospitals to schedule a biopsy-led consultation and protect long-term kidney health.

Diagnosis Approach

1

Comprehensive Lab Panel

Urine protein quantification, serum albumin, lipids, complements, ANA, and autoantibodies.

2

Imaging & Ultrasound

Renal ultrasound with Doppler to rule out structural issues or renal vein thrombosis.

3

Ultrasound-Guided Kidney Biopsy

Real-time imaging, minimal complications, samples analysed with IF and EM where indicated.

4

Pathology Review Board

Nephrologist-pathologist conference determines specific regimen based on biopsy findings.

Treatment Options

Immunosuppressive Protocols

Steroid regimens, calcineurin inhibitors, MMF, or rituximab tailored per histology.

Induces remission in 80-90% of responsive cases.
6-12 months induction with maintenance

Plasma Exchange & Immunotherapy

For severe crescentic GN or anti-GBM disease with ICU support.

Improves renal survival by 25% in severe cases.
5-7 sessions over 2 weeks

ACEi/ARB & Supportive Care

Proteinuria reduction, diuretics for oedema, and statins for dyslipidaemia.

Reduces proteinuria by 40%.
Long-term

Infection & Vaccination Shield

Pneumococcal, influenza, varicella vaccines and prophylactic antibiotics during immunosuppression.

Lowers serious infection risk below 5%.
Per protocol schedule

Lifestyle & Nutrition Guidance

Low-salt, adequate protein diet with fluid management, education in Telugu, Hindi, and Urdu.

Reduces oedema and supports remission.
Ongoing

Relapse Prevention Clinic

Self-monitoring training, home urine dipsticks, and tele follow-up for early detection.

Cuts relapse severity by 50%.
Monthly check-ins for first year

Expected Outcomes

Treatment Timeline

First 2 Weeks

Biopsy diagnosis and initiation of therapy

6-8 Weeks

Proteinuria reduction and improved albumin levels

3-6 Months

Clinical remission with stabilised kidney function

1 Year+

Low relapse rates with maintenance and monitoring

Success Metrics

  • Urine protein <0.5 g/day
  • Serum albumin >3.5 g/dL
  • Stable eGFR